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Intra-Muscular Injections

Step-By-Step Instructions for Reconstitution and Intra-muscular Administration

Intra-muscular injection requires another person to administer the injection. These instructions will help you and your partner prepare and inject your medication at home. If you have any questions, don't hesitate to call us at 800-998-4567.

Before you start
  • Wash your hands with an antibacterial soap and use alcohol to clean the area you will be working on.
  • Have these supplies ready:
    • A vial (or vials) of LG Follimon™ and/or LG IVF-M™, 75 IU, and a vial of Sodium Chloride 0.9% (sterile diluent) that is conveniently packaged with LG Follimon™ and LG IVF-M™, or LG IVF-C™ and a vial of Bacteriostatic Water (sterile diluent) that is conveniently packaged with LG IVF-C™.
    • A syringe and sterile needles (check with your doctor about which syringe and needle size to use).
    • Alcohol pads, rubbing alcohol, and gauze.
    • A needle disposal container.

Preparing your medicine and filling the syringe Remember: Only the Sodium Chloride (sterile diluent) provided must be used to reconstitute LG Follimon™ and/or LG IVF-M™ and only the Bacteriostatic Water (sterile diluent) provided must be used to reconstitute LG IVF-C™.
  • Remove syringe and needle from the wrapper. While holding the protective cap, twist needle clockwise to make sure needle is secure. Set the syringe aside.
  • Remove the plastic caps from the tops of the vials of LG Follimon™, LG IVF-M™, or LG IVF-C™ and the sterile diluent.
  • Wipe the tops of the vials with alcohol. Don't touch the tops of the vials once you have wiped them.
  • Uncap the needle by carefully twisting the needle cap clockwise and pulling the cap upward. Avoid twisting the needle counterclockwise, as this can cause the needle to separate from the syringe.
  • Insert the needle through the rubber stopper of the sterile diluent vial.
  • Do not tap the point of the needle against the sides or bottom of the vial because it may dull or bend the tip.
  • Tip the sterile diluent vial and, with the needle in the fluid, pull back on the plunger to withdraw the fluid into the syringe up to the amount instructed by your doctor.
  • Withdraw the needle from the sterile diluent fluid vial. Slowly inject the sterile diluent into the vial containing the LG Follimon™, LG IVF-M™, or LG IVF-C™ powder, aiming the sterile diluent at the side of the vial to avoid creating bubbles.
  • The LG Follimon™, LG IVF-M™, or LG IVF-C™ powder will dissolve quickly. Gently swirl until the powder is completely dissolved. Do not shake the vial because this will create bubbles.
  • As soon as the powder has completely dissolved, withdraw all the LG Follimon™, LG IVF-M™, or LG IVF-C™ solution into the syringe. There are two ways of doing this:
    1. Leave the vial on the counter, tilt it, pull back on the plunger to withdraw all the solution, or
    2. Turn the vial upside down, pull back on the plunger to withdraw the solution as you slowly lower the needle.
      Note: For patients who need multiple vials, the LG Follimon™ and/or LG IVF-M™ solution may be used to dissolve up to 5 additional vials. For those who need multiple vials, after reconstituting the first vial of LG Follimon™ and/or LG IVF-M™ with sterile diluent, use that same solution to reconstitute the additional vials of LG Follimon™ and/or LG IVF-M™. This does not apply to LG IVF-C™.
  • Hold syringe straight up. Draw back slightly on plunger and tap syringe so that any air bubbles rise to top. Slowly press plunger until all air is out of syringe and a small drop of solution forms at tip of needle.
  • Tap the syringe to remove the drop of solution at the tip of the needle.
  • Carefully recap needle to keep it sterile.
  • The LG Follimon™, LG IVF-M™, or LG IVF-C™ solution is now ready for injection.

If an uncapped needle EVER comes into contact with anything other than the LG Follimon™, LG IVF-M™, LG IVF-C™, or sterile diluent, do not inject yourself with it. Immediately remove the needle and replace it with a new sterile needle.

Preparing the injection site
  • LG Follimon™, LG IVF-M™, or LG IVF-C™ should be injected into the muscle of either the right or left upper buttock, below the hipbone. Below, we will describe a left-side injection.
  • To locate an injection site, stand directly behind the person who is to receive the injection. Imagine that the left buttock is divided into quadrants. The injection should be given in the upper left-hand corner of the upper left-hand quadrant (see diagram).
  • Swab the area with alcohol, and allow it to air-dry.
  • To relax the muscle, try standing pigeon-toed or bending your leg slightly, placing your weight on your other foot.

Injecting your medicine
  • Uncap the needle and insert it straight into the skin--in one smooth motion--until the needle disappears.
  • To make sure you haven't hit a blood vessel, pull back a little on the plunger. If you don't see blood in the syringe, you can proceed with the injection.

    If you see blood in the syringe, withdraw the needle and replace the needle with a new one. Then repeat the injection process.

  • Slowly push the plunger all the way in, until you have injected all the LG Follimon™, LG IVF-M™, or LG IVF-C™.
  • Pull the syringe straight out--again, using one smooth motion.

Dispose of the syringe and needles
  • Safely dispose of all used syringes in a needle disposal container with a lid. Extra sterile diluent or unused medication left in the vial should be thrown away. After you finish your course of treatment, ask your healthcare provider how to properly dispose of the needle disposal container.

After the injection
  • If you have a little bleeding after the injection, don't worry. Just press the site with gauze for about 10 seconds, and cover it with an adhesive bandage.



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