• Wash your hands with an antibacterial soap and use alcohol to clean the area you will be working on.
• Have these supplies ready:
  • A vial (or vials) of LG Follimon™ and/or LG IVF-M™, 75 IU, and a vial of Sodium Chloride 0.9% (sterile diluent) that is conveniently packaged with your medicine.
  • A syringe and sterile needles (check with your doctor about which syringe and needle size to use).
  • Alcohol pads, rubbing alcohol, and gauze.
  • A needle disposal container.

Remember: Only the Sodium Chloride (sterile diluent) provided must be used to reconstitute LG Follimon™ and/or LG IVF-M™.

• Remove the syringe and the larger needle from the wrapper. While holding the protective cap, twist the needle clockwise to make sure the needle is secure. Set the syringe aside.
• Remove the plastic caps from the tops of the vials of LG Follimon™ and/or LG IVF-M™ and the sterile diluent.
• Wipe the tops of the vials with alcohol. Don't touch the tops of the vials once you have wiped them.
• Uncap the needle by carefully twisting the needle cap clockwise and pulling the cap upward. Avoid twisting the needle counterclockwise, because this can cause the needle to separate from the syringe.
• Insert the needle through the rubber stopper of the sterile diluent vial.
• Tip the sterile diluent vial and, with the needle in the fluid, pull back on the plunger to withdraw the fluid into the syringe up to the amount instructed by your doctor.
• Withdraw the needle from the sterile diluent fluid vial. Slowly inject the sterile diluent into the vial containing the LG Follimon™ or LG IVF-M™ powder, aiming the sterile diluent at the side of the vial to avoid creating bubbles.
• The LG Follimon™ or LG IVF-M™ powder will dissolve quickly. Gently swirl until the powder is completely dissolved. Do not shake the vial because this will create bubbles.
• As soon as the powder has completely dissolved, withdraw all the LG Follimon™ or LG IVF-M™ solution into the syringe. There are two ways of doing this:
  1. Leave the vial on the counter, tilt it, pull back on the plunger to withdraw all the solution, or
  2. Turn the vial upside down, pull back on the plunger to withdraw the solution as you slowly lower the needle.
     Note: For patients who need multiple vials, the LG Follimon™ and/or LG IVF-M™ solution may be used to dissolve up to 5 additional vials. For those who need multiple vials, after reconstituting the first vial of LG Follimon™ and/or LG IVF-M™ with sterile diluent, use that same solution to reconstitute the additional vials of LG Follimon™ and/or LG IVF-M™.

• While holding the syringe pointing upward, replace the needle cap and remove the large needle by twisting it counterclockwise. Replace with the small, subcutaneous needle by twisting the small needle clockwise onto the syringe.
• Hold the syringe straight up. Draw back slightly on the plunger and tap the syringe so that any air bubbles rise to the top. Slowly press the plunger until all the air is out of the syringe and a small drop of solution forms at the tip of the needle.
• Tap the syringe to remove the drop of solution at the tip of the needle.
• Carefully recap the needle to keep it sterile.
• The solution is now ready for injection.

If an uncapped needle EVER comes into contact with anything other than the LG Follimon™, LG IVF-M™, or sterile diluent, do not inject yourself with it. Immediately remove the needle and replace it with a new sterile needle.

• LG Follimon™ and/or LG IVF-M™ should be injected into a skin fold on your abdomen a few inches below your navel...left or right. Each day, use the alternate side of your abdomen to help prevent soreness.
• Carefully clean the injection site area with an alcohol pad and allow the site to air-dry.
• Remove the needle cap from the syringe.
• Hold the syringe in one hand. Use your other hand to gently grasp a fold of skin in the injection site area between your thumb and index finger.
• Hold the syringe perpendicular (at a right angle) to the skin like a dart and quickly insert the needle all the way into the skin fold.
• Depress the plunger of the syringe with a steady motion until all the fluid is injected beneath the skin.
• Release the skin fold and pull the needle straight out.

• Recap the needle and discard the syringe and the needle into a needle disposal container with a lid.
• Extra sterile diluent or unused medication left in the vial should be thrown away. After you finish your course of treatment, ask your healthcare provider how to properly dispose of the needle disposal container.

• If any bleeding should occur, simply place a small piece of gauze over the injection site and apply gentle pressure to stop the bleeding.
• If the injection site becomes sore, applying ice for brief intervals may help relieve any discomfort.